Examining BPA’s Mechanisms of Action: The Role of c-Myc
نویسنده
چکیده
Bisphenol A (BPA) has shown an ability to disrupt endocrine signaling in some human and animal model studies, raising suspicions that it may be a factor in the development of endocrine-related disorders, including breast cancer. Animal studies appear to support that suspicion, but the precise molecular mechanisms by which BPA exposure may lead to cancer in humans are poorly understood.2,3 Previous studies have connected BPA exposure to molecular events in breast cells that are characteristic of cancer development. A new study reported in this issue of EHP implicates a gene further upstream of previously demonstrated mechanisms. BPA is used in a wide variety of products, including polycarbonate plastics, food and beverage containers, and coated papers (e.g., thermal
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عنوان ژورنال:
دوره 123 شماره
صفحات -
تاریخ انتشار 2015